The generic Frontline Plus i.e. Fipronil medication is a phenylpyrazole antiparasitic agent, which is primarily used to kill adult fleas and ticks. The working mechanism is as follows: The generic Frontline Plus i.e. Fipronil medication works by interfering with the brain and spinal cord of these insects, which results in their death.

The generic Frontline Plus i.e. Fipronil is a topical solution that collects in the oils of the skin and in the hair follicles, which is not absorbed into the body and does not circulate through the blood stream. Through the process of translocation, it is spread over the body in about 24 hours. However, the effects of Fipronil lasts for about 30 days and remains effective after bathing or swimming though shampooing should be avoided within 48 hours of application.

Moreover, the generic Frontline Plus i.e. Fipronil medication is a prescription drug and can be obtained from a veterinarian or by prescription from a veterinarian only. However, before taking Frontline Plus i.e. Fipronil medication, ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient and read it carefully. Talk to your doctor about all the possible risks of taking Frontline Plus medication. However, Frontline Plus may also be used for purposes other than those listed in this medication guide. Hence, for more information, consult your doctor and your medical pharmacist.

Follow the directions given by the doctor exactly for the usage of the Frontline Plus i.e. Fipronil medication and also read the prescription label carefully, and ask your veterinary doctor or pharmacist to explain any part that you do not understand.


Remember: Do not treat your pet on your own and do consult your veterinarian regarding the exact use of this medicine for your pets condition.

If you notice any of the symptoms, which seem severe or persistent to you for your, please contact your veterinary doctor immediately. However, your doctor may need to monitor your pet carefully for side effects and alter the doses if necessary.

Frontline Plus is generally well-tolerated. The most common side effects are: temporary redness or itching at the application site of your pet. And remember, the pet may drool if he/she licks the medicine or spray before it gets dry. Inform your doctor if you experience any of these side effects or some new side effects occur in your pet which may appear too bothersome to you.

Inform your doctor if your pet is allergic to the formulation of this medication or any other medication in any other form and also inform your veterinary doctor about any other medication you may be giving your pet in any other form, as they may affect the way this medicine works.

However, Frontline Plus may interact with other pesticides and hence avoid using them simultaneously on your pet. And acquire more information about the interactions of the Frontline Plus medication from your veterinary doctor.

In case of overdose call your local poison control center at 1-800-222-1222.
If the suffering patient has collapsed or is not breathing call local emergency services at 911. Canadian residents should call their local poison control center directly.

You may notice irritation at site of application in your pet and if it persists for few hours, bathe the animal and contact your veterinarian immediately.

Keep the medicine away from the children and pets. Also inform your doctor, if your pet is pregnant, weak, aged or breast feeding. Remember, it is very important to keep regular appointments with your veterinary doctor to study the way your pet is responding to the course. And if you notice any problems, consult with your veterinary doctor about using the Frontline Plus medication.

If you missed the Frontline Plus i.e. Fipronil medication dose for your pet, please consult to your veterinary doctor or physician for guidance and continue further.

Generic Frontline Plus is used to kill adult fleas, ticks etc. in pets like dogs and cats.

However, it may also be used to treat some other medical conditions which may be determined by your doctor accordingly and consult a pediatrician for the use of this medication in children.

The generic Frontline Plus i.e. Fipronil medication may be prescribed for other uses also and hence ask your veterinary doctor or pharmacist for more information about the Frontline Plus i.e. Fipronil medication.

Store generic Frontline Plus i.e. Fipronil, at room temperature, in a cool and dry place. Keep the medicine in the container, it came in and always keep it tightly closed. Check Expiry date without fail. Keep all medicines away from women, newborns, children and pets. Do not freeze in any case. Also, keep it away from heat, dampness and direct light. Heat or moisture may cause the medicine to break down. When the medicine is not in use or outdated it should be discarded. Take help of your pharmacist in disposing this medicine properly. In any case, do not store the Frontline Plus medication in the bathroom.

Following precautions must be taken during consuming generic Frontline Plus i.e. Fipronil:

1. Let your veterinary doctor know, if you are planning to give any prescribed or non prescribed medicines, pesticides etc. to your pet simultaneously with the generic Frontline Plus i.e. Fipronil medication.

2. Do not use the Frontline Plus i.e. Fipronil medication, if your pet has any kind of allergy to it or to any ingredients of it and consult your veterinary doctor about it and get treated accordingly.

3. Inform your doctor if your pet is pregnant or breast feeding before using Frontline Plus medication. And never use the medication on aged or weak animals.

4. Do not share the drug with other pets unless they are prescribed by the veterinary doctor themselves. And if your symptoms of side effects do not improve in few weeks or if they become worse and bothersome, check your pet’s conditions immediately with your veterinary doctor.

5. Please, use the Frontline Plus medicine in the prescribed amount for your pets and do not overdose it or use it for the longer period of time or discontinue on your own.

6. Regularly, keep your appointments with your veterinary doctor and keep an eye on the progress or side effects that your pet may be going through.

7. For more information, contact your veterinary doctor and also discuss the risks and benefits of the generic Frontline Plus. However, do not use the Top Spot on kittens or puppies less than 8 weeks of age. And remember, the spray is approved in the U.S. for use at 8 weeks of age in puppies and kittens, while the spray in other countries is approved for use in puppies and kittens as young as 2 days of age.

8. Remember: It is important that your doctor checks your progress at regular intervals. However, the duration of administration depends on the pet’s condition being treated, its response to the medication and the development of any adverse effects.

9. And do not forget to treat all pets in the household for fleas, and treat the environment, or the problem may reoccur and for best results keep treating your pet as often as your veterinary doctor asks you to do so.