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| Gastro Health» ESOMEPRAZOLE ess-oh-MEP-ra-zole | ||||||||||||||
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Nexium Generic
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 | descriptionsEsomeprazole is in a class of drugs called proton pump inhibitors PPIs which block the production of acid by the stomach. Other drugs in the same class include omeprazole Prilosec lansoprazole Prevacid rabeprazole Aciphex and pantoprazole Protonix. Chemically esomeprazole is very similar to omeprazole. Proton pump inhibitors are used for the treatment of conditions such as stomach and duodenal ulcers gastroesophageal reflux disease GERD and the Zollinger-Ellison syndrome which all are caused by stomach acid. Esomeprazole like other proton-pump inhibitors blocks the enzyme in the wall of the stomach that produces acid. By blocking the enzyme the production of acid is decreased and this allows the stomach and esophagus to heal. Esomeprazole was approved by the FDA in February 2001. |
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 | how to use For GERD 20 or 40 mg of esomeprazole is given once daily for 4-8 weeks. For the treatment of H. pylori 40 mg is administered once daily in combination with amoxicillin and clarithromycin for 10 days. Esomeprazole capsules should be administered one hour before meals swallowed whole and should not be crushed or chewed. Patients with difficulty swallowing can open the capsule and mix the pellets with applesauce. The applesauce should not be hot and the pellets should not be chewed or crushed. |
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 | side effectsEsomeprazole like other PPIs is well-tolerated. The most common side effects are diarrhea nausea vomiting headaches rash and dizziness. Nervousness abnormal heartbeat muscle pain weakness leg cramps and water retention occur infrequently. |
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 | interactionEsomeprazole potentially can increase the concentration in blood of diazepam Valium by decreasing the elimination of diazepam in the liver. Esomeprazole may have fewer drug interactions than omeprazole. The absorption of certain drugs may be affected by stomach acidity. Therefore esomeprazole and other PPIs that reduce stomach acid also reduce the absorption and concentration in blood of ketoconazole Nizoral and increase the absorption and concentration in blood of digoxin Lanoxin. This may lead to reduced effectiveness of ketoconazole or increased digoxin toxicity respectively. |
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 | usesEsomeprazole is approved for the treatment of gastroesophageal reflux disease GERD and in combination with amoxicillin and clarithromycin Biaxin for the treatment of patients with ulcers and H. pylori infection. Since it is very similar to omeprazole it also is likely that it will be used for the treatment of Zollinger-Ellison syndrome. |
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 | storageStore at room temperature 15-30°C 59-86°F in a tightly closed container. |
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Special Disclaimer :Images used above represent popular brands and are not the same shipped by us. We ship FDA approved generic drugs.
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